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n-Nitroso Compounds In Meat
17 Mar 2022
Disclaimer
Processed meat was classified as an IARC Group 1 Carcinogen in 2015 — see the article Processed Meat for details.

Source: Carcinogenicity of Consumption of Red and Processed Meat by Bouvard et al, The Lancet Oncology, 2015, 16 (16), pp.1599-1600 (PDF)
N-Nitroso-Compounds (NOC)

How harmful are these compounds? How are they produced in our body?

Articles by Dr Greger:

Videos by Dr Greger:

(2014) Can Diet Protect Against Kidney Cancer?

(5 mins) Transcript. A fast-paced and information rich video for which it would be helpful to watch Nitrates & Nitrites Playlist (2012) first. An excerpt from the video:

"Nitrite from all animal sources, not just processed meats, was associated with an increased risk of kidney cancer. The researchers found no associations with nitrate or nitrite intake from plant sources."

(2021) Heme-Induced N-Nitroso Compounds and Fat Oxidation

(6 mins) Transcript. Dr Greger's summary: "What do clinical studies show about the role of heme in the formation of a class of carcinogenic compounds?"

(2021) What About the Heme in Impossible Burgers?

(5 mins) Transcript. Dr Greger's summary: "Is heme just an innocent bystander in the link between meat intake and breast cancer, diabetes, heart disease, stroke, and high blood pressure?"

(2020) The Efficacy and Safety of Creatine for High Homocysteine

(7 mins) Transcript. Dr Greger's summary: "Those on a healthy plant-based diet with elevated homocysteine levels despite taking sufficient vitamin B12 may want to consider taking a gram a day of contaminant-free creatine."

(2022) Cancer-Causing NDMA in Medications (Zantac, Metformin) and Meat

(5 mins) Transcript. Dr Greger's summary: "Billion-dollar drugs pulled from the market for carcinogenic contamination less than that found in a single serving of grilled chicken."

(2021) Does Heme Iron Cause Cancer?

(5 mins) Transcript. Dr Greger's summary: "Laboratory models suggest that extreme doses of heme iron may be detrimental, but what about the effects of nutritional doses in humans? A look at heme's carcinogenic effects."

(2021) Is Heme Iron the Reason Meat Is Carcinogenic?

(7 mins) Transcript. Dr Greger's summary: "Rectal biopsies taken before and after eating meat determine the potentially DNA-damaging dose of heme."

(2012) Bacon & Botulism

(2 mins) Transcript. Dr Greger's summary: "The nitrite preservatives in processed meats such as bologna, bacon, ham, and hot dogs form carcinogenic nitrosamines, but also reduce the growth of botulism bacteria — forcing regulators to strike a balance between consumers risking cancer, or a deadly form of food poisoning."

(2012) When Nitrites Go Bad

(2 mins) Transcript. Dr Greger's summary: "Nitrites in processed meat form nitrosamines, a class of potent carcinogens found in cigarette smoke, which may explain why hot dog consumption has been associated with the two leading pediatric cancers, brain tumors and childhood leukemia."

(2012) Prevention Is Better Than Cured Meat

(2 mins) Transcript. Dr Greger's summary: "The levels of nitrosamines — considered the most carcinogenic agents in cigarette smoke — were recently measured in an array of processed meats including chicken, turkey, and pork."

(2012) Carcinogens in the Smell of Frying Bacon

(2 mins) Transcript. Dr Greger's summary: "Frying bacon outdoors decreases the concentration of airborne nitrosamine carcinogens."

(2016) Meat Industry Reaction to New Cancer Guidelines

(4 mins) Transcript. Dr Greger's summary: "What was the meat industry's response to the recommendation by leading cancer charities to stop eating processed meats, such as bacon, ham, hot dogs, sausage, and lunchmeat?"

(2021) How Our Gut Bacteria Can Use Eggs to Accelerate Cancer

(6 mins) Transcript. Dr Greger's summary: "The reason egg consumption is associated with elevated cancer risk may be the TMAO, considered the 'smoking gun' of microbiome-disease interactions."

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