Source: Offset 1:50 of Alzheimer's & Atherosclerosis of the Brain (6 mins, 2015) by Dr Greger.

Dr Greger's article on Alzheimer's Disease explains:

(3 mins) Transcript. Dr Greger's summary: "Diet may explain the Nigerian Paradox, where they have among the highest rates of the Alzheimer's susceptibility gene, ApoE4, but among the lowest rates of Alzheimer's disesae."

(4 mins) Transcript. Dr Greger explains that Alzheimer's is similar to heart disease in that 'plaques and tangles' characteristic of the disease start forming decades earlier — as early as our 20s — just like plaques form inside our coronary arteries, but remains clinically silent.

(6 mins) Transcript. This video summarizes research in 2000s and 2010s that studies the relationship between arterial clogging and onset of Alzheimer's. Some researchers have started proposing that Alzheimer's be reclassified as a vascular disorder instead of degenerative brain disease.

(4 mins) Transcript. A fascinating video by Dr Greger that I encourage my friends to watch! It has insights into how clogging of arteries affects our brain. Sometimes, when blood stops flowing in the narrowest of brain blood vessels, we get tiny "holes" in our brain (because blood supply stops and some brain tissue dies). Oh boy! Dr Greger also mentions how hypertension is associated with brain shrinkage and degenerative diseases like Alzheimer's and dementia. Summary: let's eat healthy to protect our brain from dying (and developing "holes") as we age!

Related blog article from July 2020: High Blood Pressure May Lead to Low Brain Volume

An insightful video in which Dr Peter Rogers explains the relationship between arterial clogging, blood flow, brain shrinkage and Alzheimer's.