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Cruciferous Veggies & Autism
22 Nov 2020
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Dr Greger has fascinating videos showcasing the effects of sulforaphane found in broccoli and other cruciferous veggies on autism symptoms. For example, he says:

"One food may be able to combat all four purported causal factors of autism: synaptic dysfunction, oxidative stress, mitochondrial dysfunction, and neuroinflammation."

Articles by Dr Greger:

Videos by Dr Greger:

(2020) The Best Foods for Fighting Autism and Brain Inflammation

(12 mins) Transcript. Dr Greger's summary: "The sulforaphane found in five cents' worth of broccoli sprouts has been shown to benefit autism in a way no drug ever has in randomized, double-blind, placebo-controlled study."

(2017) Fighting Autism Brain Inflammation with Food

(7 mins) Transcript. Dr Greger's summary: "One food may be able to combat all four purported causal factors of autism: synaptic dysfunction, oxidative stress, mitochondrial dysfunction, and neuroinflammation."

A highly technical video. ASD (Autism Spectrum Disorder, which affects about 1% to 1.5% of children in USA) is said to be due to 4 pathways: (a) synaptic dysfunction in our brain, (b) oxidative stress in our brain, (c) mitochondrial dysfunction, and (d) inflammation in the brain (neuroinflammation). Dr Greger explains that we have research showing that sulforaphane from broccoli and broccoli sprouts influences all four of these mechanisms positively! That's nothing short of magic!

[Dr Greger squeals in delight as he explains these surprising efficacy of a single food source at affecting disparate mechanisms causing autism; he also explains that drugs typically target one specific mechanism, not so many together. In his own words, "Give someone with autism broccoli, and heat shock proteins are released to boost synaptic transmission, Nrf2 is activated to wipe out the free radicals, mitochondrial function is restored, and we suppress the inflammation triggered by NF-kappa-beta. One food to counter all four purported causal factors."]

(2017) Fever Benefits for Autism in a Food

(7 mins) Transcript. Dr Greger's summary: "Dramatic improvements in autistic children when they have a fever suggest that the disease may be reversible if one can replicate the phenomenon in other ways."

This video builds upon the previous video ("Fighting Brain Inflammation with Food") in which 4 different mechanisms were described that are postulated to trigger autism. This video explains one specific mechanism — "synaptic function and Heat Shock Proteins (HSP)".

Okay! What's going on? Turns out that in times of fever, autistic traits reduce dramatically! This has been observed by parents and caregivers over the decades. Surprisingly, this was never documented / researched until very recently. Next, the focus of research became: what exactly happens inside our body during fever? A promising line of approach has emerged: in times of fever, our brain produces Heat Shock Proteins (HSPs) which protect and sustain synaptic function. And surprisingly, there is a food source that makes this happen naturally: broccoli and broccoli sprouts — they have sulfurophane which boosts HSP production (without inducing any fever)!

(2017) Best Foods for Autism

(6 mins) Transcript. Summary: "The sulforaphane found in five cents' worth of broccoli sprouts has been shown to benefit autism in a way no drug ever has in randomized, double-blind, placebo-controlled study."

At 4:56, Dr Greger explains that broccoli has sulforaphane, broccoli sprouts have over 10 times more but broccoli pills, powders and supplements has very little sulforaphane.

This video makes reference to TOR, a mechanism that has received a lot of attention in the last 10 years (over 5,000 research papers). Dr Greger has several articles and videos on TOR; see Animal Products & TOR Overactivation.

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