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Eggs & Gut Health (TMAO, Choline, Carnitine)
5 Nov 2021
Disclaimer
In recent years, a new mechanism has been proposed to explain heart disease and cancer: TMAO. Story in brief: (a) carnitine and choline are converted by our gut bacteria into TMAO, and (b) TMAO contributes to both heart disease and cancer. Dr Greger's videos below explain these two points in detail.

How to reduce our TMAO levels? Major dietary sources of choline and carnitine are animal products (meat, eggs, dairy). So an effective intervention for reducing TMAO levels is reduction or elimination of these animal products from our diet.

Articles by Dr Greger:

Videos by Dr Greger:

(2013) Carnitine, Choline, Cancer & Cholesterol: The TMAO Connection

(9 mins) Transcript. Fascinating video! Worth watching for a big picture understanding of {choline, carnitine} → gut bacteria → TMAO → {arterial health, cancer}.

(2017) How to Develop a Healthy Gut Ecosystem

(5 mins) Transcript. Dr Greger's summary: "What we eat determines what kind of bacteria we foster the growth of in our gut, which can increase or decrease our risk of some of our leading killer diseases."

(2021) How Our Gut Bacteria Can Use Eggs to Accelerate Cancer

(6 mins) Transcript. Dr Greger's summary: "The reason egg consumption is associated with elevated cancer risk may be the TMAO, considered the 'smoking gun' of microbiome-disease interactions."

(2017) How to Reduce Your TMAO Levels

(7 mins) Transcript.

Companion article: How to Reduce Your TMAO Levels (2021).

(2021) Can Vegan Fecal Transplants Lower TMAO Levels?

(6 mins) Transcript. Dr Greger's summary: "If the microbiome of those eating plant-based diets protects against the toxic effects of TMAO, what about swapping gut flora?"

(2013) Eggs, Choline & Cancer

(4 mins) Transcript. Dr Greger's summary: "Choline may be the reason egg consumption is associated with prostate cancer progression and death."

(2013) Eggs & Choline: Something Fishy

(5 mins) Transcript. Dr Greger's summary: "Too much choline — a compound concentrated in eggs and other animal products — can make bodily secretions smell like rotting fish, and may increase the risk of heart disease, due to conversion in the gut to trimethylamine."

(2016) Egg Industry Response to Choline & TMAO

(6 mins) Transcript. Dr Greger's summary: "How the egg industry funded a study designed to cover up the toxic trimethylamine oxide reaction to egg consumption."

(2017) How to Treat Heart Failure and Kidney Failure with Diet

(6 mins) Transcript. Dr Greger's summary: "One way a diet rich in animal-sourced foods like meat, eggs, and cheese may contribute to heart disease, stroke, kidney failure, and death is through the production of toxin called TMAO."

Dr Esselstyn
(14 mins, 2018) Dr Esselstyn: Eating Fish Gives You Highest Rate Of TMAO. Highest Rates Of TMAO Had Most Severe Cardiovascular
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