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Dr Michael Greger on Gut Microbiome
12 Dec 2020
Disclaimer
I highly recommend my friends to watch all of Dr Greger's videos below. They helped me grasp the big picture of gut microbiome, fiber and chronic lifestyle conditions. Understanding these relationships is important. We get to understand what's going in our guts, and why it's so important to keep our guts in good health.

After watching the videos above, I'd encourage you to go through Fiber, Resistant Starch, Gastrointestinal Conditions and Autoimmune Conditions. Going through all of these subjects may sound like a lot of work. And it may be difficult work because Dr Greger's videos are often technical in nature. But trust me! It's worth the effort!

Our gut lining is a single layer of cells! I found the 80-second opening statement of this video insightful:

"Our greatest exposure to the environment, our body's greatest interface with the outside world, is not through our skin, but through the lining of our gut, which covers thousands of square feet. And in our intestine, all that separates us from the outside world is a single layer of cells, 50 millionth of a meter thick. The distance between the outside world and our bloodstream is less than the thickness of a sheet of paper."

"In contrast, here's a layer of skin. Look at that — dozens of layers of protective cells to keep the outside world, outside of our bodies. Why don't we have multiple layers in our gut wall? Because we need to absorb stuff from food into our body. It's a good idea for our skin to be waterproof, so we don't start leaking, but the lining of our gut has to allow for the absorption of fluids and nutrients."

(2018) We Are Human-Microbe Superorganisms
(2019) Best Foods for Colon Cancer Prevention

(6 mins) Transcript

Key points: A high fiber diet is important for healthy microbiome, one with 'good bacteria' in abundance. Dr Greger mentions that *-biotics (prebiotics, probiotics, synbiotics) and fecal transplants could boost microbiome health but he suggests that it's probably best to simply eat WFPB.

(2019) The Best Diet for Colon Cancer Prevention

(6 mins) Transcript

Fascinating video that explains a single study: Africans in rural Africa were put on a modern western diet and Americans in America were put on a rural African diet (which happens to be predominantly plant-based). Gut microbiome was studied. Within 2 weeks, colon cancer risk for those on Western diet went up; colon cancer risk for those on African diet went down.

(2015) Microbiome: The Inside Story

(5 mins) Transcript.

(2015) Prebiotics: Tending Our Inner Garden

(6 mins) Transcript.

Key point: Our guts initiate an "inflammatory response" in the absence of fiber. Apparently, our body mistakes lack of fiber for infection. Why? See the video.

(2015) What's Your Gut Microbiome Enterotype?

(4 mins) Transcript.

Key point: humans can be divided into two broad categories: those who eat lots of plants and those who eat lots of animal products simply by analyzing our gut bacteria distribution.

(2015) How to Change Your Enterotype

(4 mins) Transcript

We can change our 'enterotype' by switching between a plant-based food system and an animal product based food system. it's that simple.

(2016) Paleopoo: What We Can Learn from Fossilized Feces

(5 mins) Transcript.

Analysis of ancient poo (paleolithic poop fossils) demonstrates that we were eating a lot of fiber (a lot of plants) back then.

The same point was made by Dr Christina Warinner, an archaeological geneticist who also featured in the documentary The Game Changers. In her PCRM talk (46 mins, 2016) and her TED talk (22 mins, 2013), she explains that "Paleo" is a marketing term without any scientific backing — a meat-centric diet is not backed by archaeological or genetic evidence, she explains.

(2017) How to Become a Fecal Transplant Super Donor

(5 mins) Transcript.

(2017) How Our Gut Bacteria Can Use Eggs to Accelerate Cancer

(6 mins) Transcript.

(2017) Microbiome: We Are What They Eat

(6 mins) Transcript.

Companion article: Updating Our Microbiome Software and Hardware (2020)

Key point: when we feed fiber to our gut bacteria, they produce molecules that protect our gut lining.

(2017) How to Reduce Your TMAO Levels

(7 mins) Transcript

The most hilarious video by Dr Greger that I've come across — instead of simply fixing our food habits to reduce TMAO levels, we've devised many other pills and procedures to effectuate the same!

(2012) Fawning over Flora

(2 mins) Transcript. What protects plant-based individuals from obesity? Many theories abound. See Boosting Gut Flora without Probiotics. In this video, Dr Greger explores the theory that production of propionate (an anti-obesity compound produced by good bacteria through digestion of fiber), which we absorb back into our system, protects us from obesity.

(2012) Boosting Good Bacteria in the Colon Without Probiotics

(1 min) Transcript. Dr Greger's summary: "Certain good bacteria in our gut can turn the fiber we eat into an anti-inflammatory, anti-cancer compound — called butyrate — that we absorb back into our system. We may be able to boost the number of butyrate-producing bacteria by eating a plant-based diet."

Companion article: Boosting Gut Flora without Probiotics (January 2013).

(2012) Tipping Firmicutes to Bacteroidetes

(2 mins) Transcript. Higher ratios of bacteriodetes to firmicutes is associated with healthier weight. What may be responsible for this? Perhaps the polyphenols in fruits, green tea and vinegars.

(2015) Stool pH & Colon Cancer

(5 mins) Transcript.

(2015) Putrefying Protein & "Toxifying" Enzymes

(5 mins) Transcript.

(2015) Bowel Wars: Hydrogen Sulfide vs Butyrate

(5 mins) Transcript.

The Role Meat May Play in Triggering Parkinson's Disease

(5 mins) Transcript. Dr Greger's summary: "What does the gut have to do with developing Parkinson's disease?"

Leaky Gut
(2021) Avoid These Foods to Prevent a Leaky Gut

(6 mins) Transcript. Dr Greger's summary: "Avoid these foods for leaky gut prevention: common drugs, foods, and beverages can disrupt the integrity of our intestinal barrier."

(2021) How to Heal a Leaky Gut with Diet

(5 mins) Transcript. Dr Greger's summary: "The recommended diet for leaky gut treatment. Which foods and food components can boost the integrity of our intestinal barrier?"

(2021) Gut Dysbiosis: Starving Our Microbial Self

(5 mins) Transcript. Dr Greger's summary: "Inadequate consumption of prebiotics — the fiber and resistant starch concentrated in unprocessed plant foods — can cause a disease-promoting imbalance in our gut microbiome."

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