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Why Cruciferous? Why Broccoli?
24 Nov 2020
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Cruciferous veggies like broccoli, cabbage, kale and collards are considered amazing! A compound called sulforaphane is formed when two compounds in such veggies come together. Sulforaphane is magical! Yeah! That's the feeling I got after watching Dr Greger's videos on sulforaphane.

For an in-depth technical exposition and literature review till 2016, I chanced upon this video: Sulforaphane and Its Effects on Cancer, Mortality, Aging, Brain and Behavior, Heart Disease & More (48 mins, 2016) by Dr Rhonda Patrick. However, to grasp the big picture in simple words, Dr Greger's videos below are better.

Why Cruciferous?

Dr Greger on Live with Kelly and Ryan (2019) explains:

"Well, you know, overall greens are the healthiest vegetables, and the healthiest types of greens are the cruciferous greens, the broccoli family of vegetables like kale and collard greens, but cabbage also fits into that family. And those purple and red cabbages have the same special eyesight and brain protective antioxidants that the berries do, but at a fraction of the cost. — Dr Greger

Dr Greger's Daily Dozen Checklist (2018) explains:

"Some foods and food groups have special nutrients not found in abundance elsewhere. For example, sulforaphane, the amazing liver-enzyme detox-boosting compound, is derived nearly exclusively from cruciferous vegetables. You could eat tons of other kinds of greens and vegetables on a given day, and get no appreciable sulforaphane if you didn't eat something cruciferous." — Dr Greger

"Common cruciferous vegetables include broccoli, cabbage, collards, and kale. I recommend at least one serving a day (typically a half-cup) and at least two additional servings of greens a day — cruciferous or otherwise. Serving sizes for other greens and vegetables are a cup for raw leafy vegetables, a half-cup for other raw or cooked non-leafy vegetables, and a quarter-cup for dried mushrooms." — Dr Greger

(2007) The Healthiest Vegetables

(2 mins) Transcript. Dr Greger's summary: "The wonders of dark green leafies."

(2019) Dr Greger on Live with Kelly and Ryan

(6 mins) Transcript. Dr Greger's summary: "Watch my JanYOUary 2018 segment on Live with Kelly and Ryan."

Sulforaphane

An excerpt from Sulforaphane at NutritionFacts:

Sulforaphane is a phenolic phytonutrient with beneficial antioxidative properties. It has been shown to target breast cancer stem cells, while leaving alone the good stem cells. Sulforaphane may also reduce the mortality rate in bladder cancer patients. It may boost our liver's own detoxifying enzymes as well as protect our brain, protect our eyesight, and protect against free radicals.

Best Source of Sulforaphane: Broccoli

Sulforaphane can be obtained from all cruciferous vegetables like kale, cauliflower or kohlrabi, with broccoli being the best source by far. Broccoli sprouts may be up to 25 times more potent than regular raw broccoli.

Excerpt from Cruciferous Vegetables at NutritionFacts:

The more commonly known cruciferous vegetables include broccoli, cauliflower, and kale, but there are many others in this family, such as collard greens, watercress, bok choy, kohlrabi, rutabaga, turnips, arugula, radishes (including horseradish), wasabi, and all types of cabbage.

Cruciferous vegetables can potentially prevent DNA damage and metastatic cancer spread, activate defenses against pathogens and pollutants, help to prevent lymphoma, boost your liver detox enzymes, target breast cancer stem cells, and reduce the risk of prostate cancer progression. The component responsible for these benefits is thought to be sulforaphane, which is formed almost exclusively in cruciferous vegetables.

Beyond being a promising anticancer agent, sulforaphane may also help protect your brain and your eyesight, reduce nasal allergy inflammation, manage type 2 diabetes, and was recently found to successfully help treat autism. A placebo-controlled, double-blind, randomized trial of boys with autism found that about two to three cruciferous vegetable servings’ worth of sulforaphane a day improves social interaction, abnormal behavior, and verbal communication within a matter of weeks. The researchers, primarily from Harvard University and Johns Hopkins University, suggest that the effect might be due to sulforaphane’s role as a "detoxicant."

Dr Greger

Dr Greger has so many videos on the benefits of cruciferous veggies, especially broccoli!

Cruciferous Veggies & Cancer: Dr Greger's videos showcase remarkable properties of broccoli family of veggies (cruciferous veggies) in cancer prevention.

Cruciferous Veggies & Autism: Dr Greger says: "One food may be able to combat all four purported causal factors of autism: synaptic dysfunction, oxidative stress, mitochondrial dysfunction, and neuroinflammation." Pretty amazing!

Cruciferous Veggies & Liver Function: Dr Greger says, "Sulforaphane, the amazing liver-enzyme detox-boosting compound, is derived nearly exclusively from cruciferous vegetables."

Cruciferous Veggies & Air Pollution: Dr Greger says: "There is a food that offers the best of both worlds — significantly improving our ability to detox carcinogens like diesel fumes and decreasing inflammation in our airways — all while improving our respiratory defenses against infections."

Cruciferous Veggies & Immune System: A couple of videos by Dr Greger explaining why cruciferous veggies are helpful for bolstering immune function.

Cabbage Benefits: Videos by Dr Greger explaining cabbage benefits for osteoarthritis and engorged breasts. Plus studies specifically on cabbage for cholesterol lowering.

Misc Videos on Cruciferous Veggies: Additional videos showcasing benefits of cruciferous veggies.

How To Eat Cruciferous Veggies?

Broccoli Sprouts: Broccoli sprouts are a nutrition powerhouse. Surprisingly high amounts of sulforaphane may be derived from broccoli sprouts. Plus a specialized technique has been discovered to boost sulforaphane concentration by a whopping 3.5x!

Daily Cruciferous Intake: How To? Lots of ideas! Can we eat them raw? Are there any special instructions to follow if we cook them? What about frozen cruciferous veggies?

Can Sulforaphane Be Derived From All Cruciferous Veggies? After browsing through Dr Greger's pages on Sulforaphane and Cruciferous Vegetables, I was under the impression that sulforaphane may be derived from all cruciferous veggies. However, the interview with Jed Fahey below has left me confused.

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